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KMID : 0387919930040020133
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Korean Journal of Cytopathology
1993 Volume.4 No. 2 p.133 ~ p.139
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Fine Needle Aspiration Cytology of Presacral Chordoma -A Case Report- @AU 연수경,
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연수경
지미경/강창석/김병기/김선무/심상인
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Abstract
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Langerhans cell histiocytosis or histiocytosis X is a disease of unknown etiology characterized by proliferation of mature histiocytes. While a few descriptions of the cytologic features of eosinophilic granuloma ocurring in the bone
have
been published, reports of cytologic findings of lymph node-based Langerhans' cell histiocytosis are very rare.
We report the cytologic findings of a case of Langerhans cell histiocytosis diagnosed by fine needle aspiration cytology from the left supraclavicular and right inguinal lymph nodes in a 65-year-old male.
Cytologic smears showed chracteristic reticuloendothelial cells which have elongated. folded, grooved nuclei and abundant pale cytoplasms. Particularly. nuclei were highly irregular and multilobated. A few mitotic figures were present. The
cytologic diagnosis was confirmed by tissue biopsies from the left supraclavicular and right inguinal lymph nodes. Proliferation of histiocytes were also present in the Immunohistochemistry for S-100 protein, vimentin,
a1-antichymotrypsin
and lysozyme showed positive staining Electron microscopy disclosed Birbeck granules.
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